A network built for scale and reliability
Cencora gives customers access to the distribution infrastructure, order support, quality and regulatory expertise, and supply chain insights needed to support efficient, secure product movement. Our U.S. network helps customers manage orders, improve visibility across the supply chain, and navigate complexity.
Nationwide reach
A growing network with 25 wholesale, 1 national, and 3 specialty distribution centers
A leading distributor
Among the nation’s largest distributors, trusted by healthcare providers of every size
A connected ecosystem
Built to serve diverse sites of care, including specialty practices and emerging care models
U.S. supply chain process
We manage every step between the manufacturer and the site of care. Planning, analytics, and optimization run as a continuous cycle across our U.S. network, from medication replenishment to regulatory and compliance.
1. Manufacturer and product intake
Product and data setup and EDI connectivity with manufacturers
2. Inbound receiving
Serialized intake, increased visibility, and DSCSA verification upon arrival
3. Efficient storage and product integrity
Controlled conditions, lot level traceability, and quality standards
4. Order fulfillment
Temperature-controlled picking and certified cold-chain pack-outs
5. Transport
Shipping, routing, and carrier coordination with outbound traceability
6. Site of care delivery
Products reach your site of care with continued customer support
At a glance
Network footprint
5.8M+
total warehouse square footage
National reach
30+
distribution centers in the U.S.
Distribution expertise
108M+
annual deliveries and shipments
Investing $1 billion in our end-to-end pharmaceutical supply chain
Cencora is investing $1 billion in its U.S. pharmaceutical supply chain through 2030 to expand capacity, strengthen resilience, and modernize how medications move across the country. These investments combine new and expanded distribution infrastructure with pharmaceutical warehouse automation and digital capabilities, helping the U.S. network respond to growing demand, operate more efficiently, and support reliable access to critical therapies.
Expanding capacity and resilience
We are expanding our national footprint to add capacity, geographic, and network flexibility. A 530,000-square-foot second national distribution center in Harrison, Ohio, is expected to be fully operational by Fall 2027, significantly increasing storage capacity. A new 430,000-square-foot distribution center in Fontana, California, is expected to be fully operational by Fall 2027 and nearly double the size of the facility it will replace. Together, these investments strengthen national and regional distribution capacity.
Growing cold chain capacity for specialty pharmaceuticals
We are also expanding cold chain capacity in Dothan, Alabama, to support continued growth in specialty pharmaceuticals and the rising demand for temperature-controlled distribution. Expected to be completed by Spring 2027, this expansion will increase our refrigerated storage capacity by 500% and frozen storage capacity by 200%. These investments strengthen our ability to handle complex specialty medicines and emerging therapies.
Explore our U.S. supply chain network
Take a closer look at the infrastructure and operational capabilities behind our network. Our coordinated distribution model helps support reliable product access, strengthens continuity, and serves diverse sites of care with confidence.
More ways we support your business
The U.S. supply chain is one connected part of Cencora. Because your ordering and vaccine programs run on the same network and the same relationship, you can manage more of your business in one place, with fewer gaps between systems and one partner for your end-to-end process.
Connect with our supply chain team
Our team of supply chain experts is here to assist you. Whether you have questions or need more detailed information, don’t hesitate to get in touch. We’re dedicated to providing the support you need.
Or, if you need general support or additional contact information, visit our Contact us page.