A network built for scale and reliability
Cencora gives customers access to the distribution infrastructure, order support, quality and regulatory expertise, and supply chain insights needed to support efficient, secure product movement. Our network helps customers manage orders, improve visibility across the supply chain, and navigate complexity with resources designed to support safe handling and more informed operational planning.
Nationwide reach
25 wholesale distribution centers, 1 national distribution center, and 3 specialty distribution centers.
A leading distributor
Among the nation’s largest healthcare distributors, trusted by healthcare providers of every size.
A connected ecosystem
Built to serve manufacturer partners and diverse sites of care, including independent, retail, and long-term care pharmacies, hospitals and health systems, specialty practices such as oncology, government partners, and emerging care models.
U.S. supply chain process
Cencora manages every step between the manufacturer and the site of care. Behind every step, planning, analytics, and optimization run as a continuous cycle across the network — spanning replenishment and manufacturer operations; quality, regulatory, and DSCSA compliance; distribution operations; and customer and manufacturer support.
1. Manufacturer and product intake
Product and data setup and EDI connectivity with manufacturers.
2. Inbound receiving
Serialized intake and DSCSA verification on arrival.
3. Efficient storage and product integrity
Controlled conditions, lot level traceability, and quality standards.
4. Order fulfillment
Temperature-controlled picking and certified cold-chain pack-outs.
5. Transport
Shipping, routing, and carrier coordination with outbound traceability.
6. Site of care delivery
Product reaches your site, with customer support after receipt.
At a glance
Network footprint
5.8M+
total warehouse square footage
National reach
30+
distribution centers in the U.S.
Distribution expertise
108M+
annual deliveries and shipments
Investing $1 billion in our end-to-end pharmaceutical supply chain
Cencora is investing $1 billion in its U.S. pharmaceutical supply chain through 2030 to expand capacity, strengthen resilience, and modernize how medications move across the country. These investments combine new and expanded distribution infrastructure with pharmaceutical warehouse automation and digital capabilities, helping the network respond to growing demand, operate more efficiently, and support reliable access to critical therapies.
Expanding capacity and resilience
We are expanding our national footprint to add capacity, geographic, and network flexibility. A 530,000-square-foot second national distribution center in Harrison, Ohio, is expected to be fully operational by Fall 2027, significantly increasing storage capacity and throughput. On the West Coast, a new approximately 430,000-square-foot distribution center in Fontana, California, is expected to be fully operational by Fall 2027 and will be nearly double the size of the facility it replaces. Together, these investments strengthen national and regional distribution capacity and support business continuity, helping the network adapt as customer demand, product complexity, and patient needs continue to evolve.
Growing cold chain capacity for specialty pharmaceuticals
Cencora is also expanding cold chain capacity in Dothan, Alabama, to support continued growth in specialty pharmaceuticals and the rising demand for temperature-controlled distribution. Expected to be completed by Spring 2027, the expansion will increase refrigerated storage capacity by 500% and frozen storage capacity by 200%. These investments strengthen Cencora’s ability to handle complex specialty medicines while supporting greater supply chain resilience as more therapies require specialized storage, handling, and transport.
Explore our U.S. supply chain network
Take a closer look at the reach, infrastructure, and operational capabilities behind our U.S. supply chain network to learn how our coordinated distribution model helps support reliable product access, strengthen continuity, and serve sites of care with greater consistency and confidence.
More ways we support your business
The U.S. supply chain is one connected part of Cencora. Because your ordering and vaccine programs run on the same network and the same relationship, you manage more of your business in one place, with fewer gaps between systems and one partner accountable from order to delivery.
Connect with our supply chain team
Our team of supply chain experts is here to assist you. Whether you have questions or need more detailed information, don’t hesitate to get in touch. We’re dedicated to providing the support you need.
Or, if you need general support or additional contact information, visit our Contact us page.