Why Cencora Gateway Exchange?
Independent pharmacies and covered entities face fragmented systems, manual processes, and limited visibility, which slows growth and leaves operational value on the table.
Cencora Gateway Exchange is the connectivity backbone that standardizes how 340B relationships are established, managed, and scaled across the ecosystem.
Cencora Gateway Exchange is the connectivity backbone that standardizes how 340B relationships are established, managed, and scaled across the ecosystem.
What Cencora Gateway Exchange delivers
- Centralized coordination: One connection point to coordinate 340B relationships across pharmacies, covered entities, and TPAs.
- Standardized workflows: Rules-driven onboarding and data exchange replace manual, one-off processes.
- Streamlined onboarding: A single, guided enrollment path gets stakeholders connected and live in weeks.
- Improved visibility: A shared view of relationships, claims, and operational status, tailored by stakeholder type.
- Scalable connectivity: A repeatable model that grows as you add pharmacies, covered entities, and TPA relationships.
Built for the way 340B actually works
Cencora Gateway Exchange removes the barriers that slow pharmacy participation and covered entity growth, delivering a standardized, scalable model across the entire ecosystem.
One connection
A single integration point replaces fragmented, one-off connections across pharmacies, covered entities, and TPAs.
Standardized workflows
Rules-driven processes reduce manual effort and operational variability across every stakeholder relationship.
Real-time visibility
Track claims, relationships, and operational status through a unified dashboard designed for each stakeholder type.
Built to scale
A repeatable activation model supports ongoing expansion across additional pharmacy groups, covered entities, and TPA relationships.
Built to support multiple 340B stakeholders
Cencora Gateway Exchange is designed to support coordination across the 340B ecosystem by helping covered entities, pharmacies, and third-party administrators work through a more standardized connectivity model.
Cencora Gateway Exchange
Cencora Gateway Exchange is a secure, web-based platform. After you enroll, you log in to the portal to manage your connections, exchange standardized data, and track the status of your active 340B relationships, all in one place.
The portal delivers the same infrastructure used by national chains — now available to pharmacies and covered entities in a scalable, enterprise-ready model.
The portal delivers the same infrastructure used by national chains — now available to pharmacies and covered entities in a scalable, enterprise-ready model.
Cencora Gateway Exchange works alongside your existing 340B program structure
Cencora Gateway Exchange is intended to support connectivity and coordination among participating stakeholders. It does not replace the roles and responsibilities of covered entities, third-party administrators, or participating pharmacies within the 340B program.
Cencora Gateway Exchange does not:
Cencora Gateway Exchange does not:
- Determine 340B eligibility
- Administer a 340B program
- Replace a third-party administrator
- Modify Health Resources and Services Administration requirements
- Manage accumulators, compliance activities, or program oversight
Frequently asked questions
No. Cencora Gateway Exchange is designed to support connectivity and coordination. Third-party administrators remain responsible for core 340B program administration activities, including eligibility determinations, program configuration, reporting, and oversight.
Most pharmacies can be connected and live within a few weeks, depending on integrations and stakeholder readiness.
No. Cencora Gateway Exchange does not determine eligibility, administer a 340B program, or modify Health Resources and Services Administration requirements.