Addressing generic drug shortages: Contributing factors and public policy recommendations

Generic drug shortages—including both sterile injectables and oral solids—negatively impact millions of patients and healthcare providers across the U.S. These shortages are complex and require coordinated public-private efforts to identify contributing factors and develop effective policy solutions. As a vital member of the pharmaceutical supply chain, Cencora aims to collaborate with federal and state policymakers, regulators, and the Administration to enhance care delivery, improve reimbursement processes, and increase supply chain transparency and resilience.

This white paper outlines recommended approaches to combat generic drug shortages and improve patient access and outcomes, while improving U.S. national security. These recommendations are categorized into three main themes:

• Short-term solutions - Sustainable and reliable manufacturing
• Mid-term solutions - Increasing stability of supply: Supply assurance programs
• Long-term solutions - Improving the resilience of the domestic supply chain and diversification of sources: Tax incentives