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International Reference Pricing (IRP): Foundations, shifts, and what to do next

Understand how IRP shapes pricing in 75+ markets, what’s driving policy shifts, and how to adapt global launch and access strategies.

Key highlights

This white paper explains how IRP is used to set medicine prices across more than 75 markets, why policies are shifting (including new U.S. MFN-style models and moves toward confidential pricing), and what these changes mean for affordability, access, innovation, and global launch strategy.